The objective of this Project is to predict treatment outcome for injured runners using baseline gait biomechanics and patient reported outcome (PRO) data. In Canada, running is the number one recreational activity and has substantial benefits including improved quality of life (QoL), fitness, and health. However, each year 48%-65% of runners sustain a musculoskeletal (MSK) injury: the leading cause of disability for individuals under age 45. Patellofemoral pain (PFP) is the most common MSK injury with a combined direct and indirect cost of $145M-$182M per year in novice runners alone. PFP results in significantly reduced activity and QoL, along with an increased risk of chronic disease. Therefore, an interdisciplinary approach is critical to develop optimal treatment strategies to provide the right patients the right treatment at the right time.